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The conserved DNMT1-dependent methylation regions in human cells are vulnerable to neurotoxicant rotenone exposure
BACKGROUND: Allele-specific DNA methylation (ASM) describes genomic loci that maintain CpG methylation at only one inherited allele rather than having coordinated methylation across both alleles. The most prominent of these regions are germline ASMs (gASMs) that control the expression of imprinted g...
Autores principales: | Freeman, Dana M., Lou, Dan, Li, Yanqiang, Martos, Suzanne N., Wang, Zhibin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076959/ https://www.ncbi.nlm.nih.gov/pubmed/32178731 http://dx.doi.org/10.1186/s13072-020-00338-8 |
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