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MethylNet: an automated and modular deep learning approach for DNA methylation analysis

BACKGROUND: DNA methylation (DNAm) is an epigenetic regulator of gene expression programs that can be altered by environmental exposures, aging, and in pathogenesis. Traditional analyses that associate DNAm alterations with phenotypes suffer from multiple hypothesis testing and multi-collinearity du...

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Detalles Bibliográficos
Autores principales: Levy, Joshua J., Titus, Alexander J., Petersen, Curtis L., Chen, Youdinghuan, Salas, Lucas A., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076991/
https://www.ncbi.nlm.nih.gov/pubmed/32183722
http://dx.doi.org/10.1186/s12859-020-3443-8