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miR-34a targets PAI-1 to regulate urinary microalbumin and renal function in hypertensive mice

BACKGROUND: The aim of the study is to investigate the effects of miR-34a targeted at PAI-1 on urinary microalbumin and renal function in hypertensive mice. METHODS: Twenty specific-pathogen-free (SPF) BPN/3J mice were selected in normal group, and 120 SPF BPH/2J mice were evenly divided into model...

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Detalles Bibliográficos
Autores principales: Liu, Ruitao, Yang, Lihong, Wei, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077132/
https://www.ncbi.nlm.nih.gov/pubmed/32178735
http://dx.doi.org/10.1186/s40001-020-00404-7