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On rare variants in principal component analysis of population stratification
BACKGROUND: Population stratification is a known confounder of genome-wide association studies, as it can lead to false positive results. Principal component analysis (PCA) method is widely applied in the analysis of population structure with common variants. However, it is still unclear about the a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077175/ https://www.ncbi.nlm.nih.gov/pubmed/32183706 http://dx.doi.org/10.1186/s12863-020-0833-x |