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On rare variants in principal component analysis of population stratification

BACKGROUND: Population stratification is a known confounder of genome-wide association studies, as it can lead to false positive results. Principal component analysis (PCA) method is widely applied in the analysis of population structure with common variants. However, it is still unclear about the a...

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Detalles Bibliográficos
Autores principales: Ma, Shengqing, Shi, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077175/
https://www.ncbi.nlm.nih.gov/pubmed/32183706
http://dx.doi.org/10.1186/s12863-020-0833-x