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Efficacy and Safety of OnabotulinumtoxinA 400 Units in Patients with Post-Stroke Upper Limb Spasticity: Final Report of a Randomized, Double-Blind, Placebo-Controlled Trial with an Open-Label Extension Phase

In many countries, 400 units (U) is the maximum dose of onabotulinumtoxinA available to treat upper limb spasticity, but few studies have demonstrated the optimal use of this dose. In the double-blind phase of this randomized, controlled trial, we compared the efficacy and safety of 400 vs. 240 U on...

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Detalles Bibliográficos
Autores principales: Abo, Masahiro, Shigematsu, Takashi, Hara, Hiroyoshi, Matsuda, Yasuko, Nimura, Akinori, Yamashita, Yoshiyuki, Takahashi, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077183/
https://www.ncbi.nlm.nih.gov/pubmed/32085529
http://dx.doi.org/10.3390/toxins12020127