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Characterization of Adenovirus 5 E1A Exon 1 Deletion Mutants in the Viral Replicative Cycle

Human adenovirus infection is driven by Early region 1A (E1A) proteins, which are the first proteins expressed following the delivery of the viral genome to the cellular nucleus. E1A is responsible for reprogramming the infected cell to support virus replication alongside the activation of expressio...

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Detalles Bibliográficos
Autores principales: Costa, Rita, Akkerman, Nikolas, Graves, Drayson, Crisostomo, Leandro, Bachus, Scott, Pelka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077205/
https://www.ncbi.nlm.nih.gov/pubmed/32075072
http://dx.doi.org/10.3390/v12020213