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Mechanism of Action of Botulinum Toxin A in Treatment of Functional Urological Disorders

Intravesical botulinum toxin (BoNT) injection is effective in reducing urgency and urinary incontinence. It temporarily inhibits the detrusor muscle contraction by blocking the release of acetylcholine (Ach) from the preganglionic and postganglionic nerves in the efferent nerves. BoNT-A also blocks...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Hua, Chiang, Bing-Juin, Liao, Chun-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077222/
https://www.ncbi.nlm.nih.gov/pubmed/32085522
http://dx.doi.org/10.3390/toxins12020129