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Measles Vaccines Designed for Enhanced CD8(+) T Cell Activation

Priming and activation of CD8(+) T cell responses is crucial to achieve anti-viral and anti-tumor immunity. Live attenuated measles vaccine strains have been used successfully for immunization for decades and are currently investigated in trials of oncolytic virotherapy. The available reverse geneti...

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Detalles Bibliográficos
Autores principales: Busch, Elena, Kubon, Kristina D., Mayer, Johanna K. M., Pidelaserra-Martí, Gemma, Albert, Jessica, Hoyler, Birgit, Heidbuechel, Johannes P. W., Stephenson, Kyle B., Lichty, Brian D., Osen, Wolfram, Eichmüller, Stefan B., Jäger, Dirk, Ungerechts, Guy, Engeland, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077255/
https://www.ncbi.nlm.nih.gov/pubmed/32098134
http://dx.doi.org/10.3390/v12020242