Cargando…

Porcine Epidemic Diarrhea Virus (PEDV) ORF3 Enhances Viral Proliferation by Inhibiting Apoptosis of Infected Cells

The genomes of coronaviruses carry accessory genes known to be associated with viral virulence. The single accessory gene of porcine epidemic diarrhea virus (PEDV), ORF3, is dispensable for virus replication in vitro, while viral mutants carrying ORF3 truncations exhibit an attenuated phenotype of w...

Descripción completa

Detalles Bibliográficos
Autores principales: Si, Fusheng, Hu, Xiaoxia, Wang, Chenyang, Chen, Bingqing, Wang, Ruiyang, Dong, Shijuan, Yu, Ruisong, Li, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077256/
https://www.ncbi.nlm.nih.gov/pubmed/32075094
http://dx.doi.org/10.3390/v12020214