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Porcine Epidemic Diarrhea Virus (PEDV) ORF3 Enhances Viral Proliferation by Inhibiting Apoptosis of Infected Cells
The genomes of coronaviruses carry accessory genes known to be associated with viral virulence. The single accessory gene of porcine epidemic diarrhea virus (PEDV), ORF3, is dispensable for virus replication in vitro, while viral mutants carrying ORF3 truncations exhibit an attenuated phenotype of w...
Autores principales: | Si, Fusheng, Hu, Xiaoxia, Wang, Chenyang, Chen, Bingqing, Wang, Ruiyang, Dong, Shijuan, Yu, Ruisong, Li, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077256/ https://www.ncbi.nlm.nih.gov/pubmed/32075094 http://dx.doi.org/10.3390/v12020214 |
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