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Generation of Simian Rotavirus Reassortants with VP4- and VP7-Encoding Genome Segments from Human Strains Circulating in Africa Using Reverse Genetics

Human rotavirus A (RVA) causes acute gastroenteritis in infants and young children. The broad use of two vaccines, which are based on RVA strains from Europe and North America, significantly reduced rotavirus disease burden worldwide. However, a lower vaccine effectiveness is recorded in some region...

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Detalles Bibliográficos
Autores principales: Falkenhagen, Alexander, Patzina-Mehling, Corinna, Gadicherla, Ashish K., Strydom, Amy, O’Neill, Hester G., Johne, Reimar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077283/
https://www.ncbi.nlm.nih.gov/pubmed/32054092
http://dx.doi.org/10.3390/v12020201