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Comparison of CRISPR and Marker-Based Methods for the Engineering of Phage T7
With the recent rise in interest in using lytic bacteriophages as therapeutic agents, there is an urgent requirement to understand their fundamental biology to enable the engineering of their genomes. Current methods of phage engineering rely on homologous recombination, followed by a system of sele...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077284/ https://www.ncbi.nlm.nih.gov/pubmed/32050613 http://dx.doi.org/10.3390/v12020193 |