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Dynamic Shifts in the HIV Proviral Landscape During Long Term Combination Antiretroviral Therapy: Implications for Persistence and Control of HIV Infections

Combination antiretroviral therapy (cART) controls but does not eradicate HIV infection; HIV persistence is the principal obstacle to curing infections. The proportion of defective proviruses increases during cART, but the dynamics of this process are not well understood, and a quantitative analysis...

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Detalles Bibliográficos
Autores principales: Anderson, Elizabeth M., Simonetti, Francesco R., Gorelick, Robert J., Hill, Shawn, Gouzoulis, Monica A., Bell, Jennifer, Rehm, Catherine, Pérez, Liliana, Boritz, Eli, Wu, Xiaolin, Wells, Daria, Hughes, Stephen H., Rao, Venigalla, Coffin, John M., Kearney, Mary F., Maldarelli, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077288/
https://www.ncbi.nlm.nih.gov/pubmed/31991737
http://dx.doi.org/10.3390/v12020136