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Dynamic Shifts in the HIV Proviral Landscape During Long Term Combination Antiretroviral Therapy: Implications for Persistence and Control of HIV Infections
Combination antiretroviral therapy (cART) controls but does not eradicate HIV infection; HIV persistence is the principal obstacle to curing infections. The proportion of defective proviruses increases during cART, but the dynamics of this process are not well understood, and a quantitative analysis...
Autores principales: | Anderson, Elizabeth M., Simonetti, Francesco R., Gorelick, Robert J., Hill, Shawn, Gouzoulis, Monica A., Bell, Jennifer, Rehm, Catherine, Pérez, Liliana, Boritz, Eli, Wu, Xiaolin, Wells, Daria, Hughes, Stephen H., Rao, Venigalla, Coffin, John M., Kearney, Mary F., Maldarelli, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077288/ https://www.ncbi.nlm.nih.gov/pubmed/31991737 http://dx.doi.org/10.3390/v12020136 |
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