Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation

In this study, we characterized the role of host cell protein tyrosyl-DNA phosphodiesterase 2 (TDP2) activity, also known as VPg unlinkase, in picornavirus infections in a human cell model of infection. TDP2/VPg unlinkase is used by picornaviruses to remove the small polypeptide, VPg (Virus Protein...

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Detalles Bibliográficos
Autores principales: Holmes, Autumn C., Zagnoli-Vieira, Guido, Caldecott, Keith W., Semler, Bert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077319/
https://www.ncbi.nlm.nih.gov/pubmed/32023921
http://dx.doi.org/10.3390/v12020166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077319/
https://www.ncbi.nlm.nih.gov/pubmed/32023921
http://dx.doi.org/10.3390/v12020166

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