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Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation

In this study, we characterized the role of host cell protein tyrosyl-DNA phosphodiesterase 2 (TDP2) activity, also known as VPg unlinkase, in picornavirus infections in a human cell model of infection. TDP2/VPg unlinkase is used by picornaviruses to remove the small polypeptide, VPg (Virus Protein...

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Detalles Bibliográficos
Autores principales:	Holmes, Autumn C., Zagnoli-Vieira, Guido, Caldecott, Keith W., Semler, Bert L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077319/ https://www.ncbi.nlm.nih.gov/pubmed/32023921 http://dx.doi.org/10.3390/v12020166

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