An Engineered Microvirin Variant with Identical Structural Domains Potently Inhibits Human Immunodeficiency Virus and Hepatitis C Virus Cellular Entry

Microvirin (MVN) is one of the human immunodeficiency virus (HIV-1) entry inhibitor lectins, which consists of two structural domains sharing 35% sequence identity and contrary to many other antiviral lectins, it exists as a monomer. In this study, we engineered an MVN variant, LUMS1, consisting of...

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Detalles Bibliográficos
Autores principales: Shahid, Munazza, Qadir, Amina, Yang, Jaewon, Ahmad, Izaz, Zahid, Hina, Mirza, Shaper, Windisch, Marc P., Shahzad-ul-Hussan, Syed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077325/
https://www.ncbi.nlm.nih.gov/pubmed/32054060
http://dx.doi.org/10.3390/v12020199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077325/
https://www.ncbi.nlm.nih.gov/pubmed/32054060
http://dx.doi.org/10.3390/v12020199

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