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An Engineered Microvirin Variant with Identical Structural Domains Potently Inhibits Human Immunodeficiency Virus and Hepatitis C Virus Cellular Entry

Microvirin (MVN) is one of the human immunodeficiency virus (HIV-1) entry inhibitor lectins, which consists of two structural domains sharing 35% sequence identity and contrary to many other antiviral lectins, it exists as a monomer. In this study, we engineered an MVN variant, LUMS1, consisting of...

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Detalles Bibliográficos
Autores principales:	Shahid, Munazza, Qadir, Amina, Yang, Jaewon, Ahmad, Izaz, Zahid, Hina, Mirza, Shaper, Windisch, Marc P., Shahzad-ul-Hussan, Syed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077325/ https://www.ncbi.nlm.nih.gov/pubmed/32054060 http://dx.doi.org/10.3390/v12020199

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