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LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes
OBJECTIVES: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synthesis. Here, we have analyzed the role of Liver X...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077358/ https://www.ncbi.nlm.nih.gov/pubmed/32210962 http://dx.doi.org/10.3389/fimmu.2020.00353 |