LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes

OBJECTIVES: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synthesis. Here, we have analyzed the role of Liver X...

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Detalles Bibliográficos
Autores principales: Sohrabi, Yahya, Sonntag, Glenn V. H., Braun, Laura C., Lagache, Sina M. M., Liebmann, Marie, Klotz, Luisa, Godfrey, Rinesh, Kahles, Florian, Waltenberger, Johannes, Findeisen, Hannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077358/
https://www.ncbi.nlm.nih.gov/pubmed/32210962
http://dx.doi.org/10.3389/fimmu.2020.00353

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