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A Chitosan-Based Micellar System as Nanocarrier For the Delivery of Paclitaxel

In this study, a redox-sensitive chitosan derivative with modifications by cholesterol, sulfhydryl, and mPEG (mPEG-CS(SH)-CHO) was successfully synthesized and characterized. Due to its amphiphilicity, the conjugate could spontaneously form micelles in an aqueous environment. The optimized paclitaxe...

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Detalles Bibliográficos
Autores principales: Han, Yang, Liang, Na, Yan, Pengfei, Kawashima, Yoshiaki, Cui, Fude, Sun, Shaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077419/
https://www.ncbi.nlm.nih.gov/pubmed/32046268
http://dx.doi.org/10.3390/polym12020380