The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation

Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles is a w...

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Detalles Bibliográficos
Autores principales: Hoang Thi, Thai Thanh, Pilkington, Emily H., Nguyen, Dai Hai, Lee, Jung Seok, Park, Ki Dong, Truong, Nghia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077443/
https://www.ncbi.nlm.nih.gov/pubmed/32024289
http://dx.doi.org/10.3390/polym12020298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077443/
https://www.ncbi.nlm.nih.gov/pubmed/32024289
http://dx.doi.org/10.3390/polym12020298

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