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The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation
Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles is a w...
Autores principales: | Hoang Thi, Thai Thanh, Pilkington, Emily H., Nguyen, Dai Hai, Lee, Jung Seok, Park, Ki Dong, Truong, Nghia P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077443/ https://www.ncbi.nlm.nih.gov/pubmed/32024289 http://dx.doi.org/10.3390/polym12020298 |
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