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Airway epithelial ITGB4 deficiency in early life mediates pulmonary spontaneous inflammation and enhanced allergic immune response

Lung immune responses to respiratory pathogens and allergens are initiated in early life which will further influence the later onset of asthma. The airway epithelia form the first mechanical physical barrier to allergic stimuli and environmental pollutants, which is also the key regulator in the in...

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Detalles Bibliográficos
Autores principales: Tang, Sha, Du, Xizi, Yuan, Lin, Xiao, Gelei, Wu, Mengping, Wang, Leyuan, Wu, ShuangYan, Duan, Zhen, Xiang, Yang, Qu, Xiangping, Liu, Huijun, Zou, Yizhou, Qin, Xiaoqun, Qin, Ling, Liu, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077534/
https://www.ncbi.nlm.nih.gov/pubmed/31970850
http://dx.doi.org/10.1111/jcmm.15000