PTBP3 promotes malignancy and hypoxia‐induced chemoresistance in pancreatic cancer cells by ATG12 up‐regulation

Pancreatic ductal adenocarcinoma (PDAC) tumours exhibit a high level of heterogeneity which is associated with hypoxia and strong resistance to chemotherapy. The RNA splicing protein polypyrimidine tract‐binding protein 3 (PTBP3) regulates hypoxic gene expression by selectively binding to hypoxia‐re...

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Detalles Bibliográficos
Autores principales: Ma, Jun, Weng, Li, Jia, Yiping, Liu, Bingyan, Wu, Shaoqiu, Xue, Lei, Yin, Xiang, Mao, Aiwu, Wang, Zhongmin, Shang, Mingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077536/
https://www.ncbi.nlm.nih.gov/pubmed/31989778
http://dx.doi.org/10.1111/jcmm.14896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077536/
https://www.ncbi.nlm.nih.gov/pubmed/31989778
http://dx.doi.org/10.1111/jcmm.14896

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