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PTBP3 promotes malignancy and hypoxia‐induced chemoresistance in pancreatic cancer cells by ATG12 up‐regulation

Pancreatic ductal adenocarcinoma (PDAC) tumours exhibit a high level of heterogeneity which is associated with hypoxia and strong resistance to chemotherapy. The RNA splicing protein polypyrimidine tract‐binding protein 3 (PTBP3) regulates hypoxic gene expression by selectively binding to hypoxia‐re...

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Detalles Bibliográficos
Autores principales:	Ma, Jun, Weng, Li, Jia, Yiping, Liu, Bingyan, Wu, Shaoqiu, Xue, Lei, Yin, Xiang, Mao, Aiwu, Wang, Zhongmin, Shang, Mingyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077536/ https://www.ncbi.nlm.nih.gov/pubmed/31989778 http://dx.doi.org/10.1111/jcmm.14896

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