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LPS‐induced inflammation desensitizes hepatocytes to Fas‐induced apoptosis through Stat3 activation—The effect can be reversed by ruxolitinib

Recent studies have established a concept of tumour necrosis factor‐α (TNF‐α)/Fas signalling crosstalk, highlighting TNF‐α as a critical cytokine in sensitizing hepatocytes to death induced by Fas activation. However, in the exact inflammatory response, besides TNF‐α, many other mediators, that migh...

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Detalles Bibliográficos
Autores principales: Markotic, Antonio, Flegar, Darja, Grcevic, Danka, Sucur, Alan, Lalic, Hrvoje, Turcic, Petra, Kovacic, Natasa, Lukac, Nina, Pravdic, Danijel, Vukojevic, Katarina, Cavar, Ivan, Kelava, Tomislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077556/
https://www.ncbi.nlm.nih.gov/pubmed/32022429
http://dx.doi.org/10.1111/jcmm.14930