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Clinically Relevant Insulin Degludec and Its Interaction with Polysaccharides: A Biophysical Examination

Protein polysaccharide complexes have been widely studied for multiple industrial applications and are popular due to their biocompatibility. Insulin degludec, an analogue of human insulin, exists as di-hexamer in pharmaceutical formulations and has the potential to form long multi-hexamers in physi...

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Detalles Bibliográficos
Autores principales: Jiwani, Shahwar Imran, Huang, Sha, Beji, Oritsegidenene, Gyasi-Antwi, Philemon, Gillis, Richard B., Adams, Gary G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077624/
https://www.ncbi.nlm.nih.gov/pubmed/32050432
http://dx.doi.org/10.3390/polym12020390