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FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas

Intraflagellar transport (IFT) is required for ciliary assembly and maintenance. While disruption of IFT may trigger ciliary disassembly, we show here that IFT mediated transport of a CDK-like kinase ensures proper ciliary disassembly. Mutations in flagellar shortening 2 (FLS2), encoding a CDK-like...

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Detalles Bibliográficos
Autores principales: Zhao, Qin, Li, Shufen, Shao, Shangjin, Wang, Zhengmao, Pan, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077844/
https://www.ncbi.nlm.nih.gov/pubmed/32134924
http://dx.doi.org/10.1371/journal.pgen.1008561