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FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas
Intraflagellar transport (IFT) is required for ciliary assembly and maintenance. While disruption of IFT may trigger ciliary disassembly, we show here that IFT mediated transport of a CDK-like kinase ensures proper ciliary disassembly. Mutations in flagellar shortening 2 (FLS2), encoding a CDK-like...
Autores principales: | Zhao, Qin, Li, Shufen, Shao, Shangjin, Wang, Zhengmao, Pan, Junmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077844/ https://www.ncbi.nlm.nih.gov/pubmed/32134924 http://dx.doi.org/10.1371/journal.pgen.1008561 |
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