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Effect of heat shock protein 70 modulators on the development of morphine analgesic tolerance in rats
The clinical use of opioid analgesics, such as morphine, is limited by analgesic tolerance, molecular mechanism of which is not well understood. Recently, molecular chaperone heat shock protein 70 (Hsp70) has been demonstrated to play important roles in morphine-induced neuroadaptation. Here, we foc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams and Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077967/ https://www.ncbi.nlm.nih.gov/pubmed/31770112 http://dx.doi.org/10.1097/FBP.0000000000000528 |