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Effect of heat shock protein 70 modulators on the development of morphine analgesic tolerance in rats

The clinical use of opioid analgesics, such as morphine, is limited by analgesic tolerance, molecular mechanism of which is not well understood. Recently, molecular chaperone heat shock protein 70 (Hsp70) has been demonstrated to play important roles in morphine-induced neuroadaptation. Here, we foc...

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Detalles Bibliográficos
Autores principales: Qin, Wangjun, Zhang, Lei, Tang, Kun, Zhao, Li, Mao, Min, Wang, Yanting, Liang, Jianhui, Zhang, Xianglin, Li, Pengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams and Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077967/
https://www.ncbi.nlm.nih.gov/pubmed/31770112
http://dx.doi.org/10.1097/FBP.0000000000000528