Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation

Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear. Here, we found that genetically silencing cerebellar Purkinje cell output blocked tremor in mice that were given the...

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Detalles Bibliográficos
Autores principales: Brown, Amanda M, White, Joshua J, van der Heijden, Meike E, Zhou, Joy, Lin, Tao, Sillitoe, Roy V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077982/
https://www.ncbi.nlm.nih.gov/pubmed/32180549
http://dx.doi.org/10.7554/eLife.51928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077982/
https://www.ncbi.nlm.nih.gov/pubmed/32180549
http://dx.doi.org/10.7554/eLife.51928

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