Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding

Mitochondria control the activity, quality, and lifetime of their proteins with an autonomous system of chaperones, but the signals that direct substrate-chaperone interactions and outcomes are poorly understood. We previously discovered that the mitochondrial AAA+ protein unfoldase ClpX (mtClpX) ac...

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Detalles Bibliográficos
Autores principales: Kardon, Julia R, Moroco, Jamie A, Engen, John R, Baker, Tania A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077987/
https://www.ncbi.nlm.nih.gov/pubmed/32091391
http://dx.doi.org/10.7554/eLife.54387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077987/
https://www.ncbi.nlm.nih.gov/pubmed/32091391
http://dx.doi.org/10.7554/eLife.54387

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