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Sonification based de novo protein design using artificial intelligence, structure prediction, and analysis using molecular modeling

We report the use of a deep learning model to design de novo proteins, based on the interplay of elementary building blocks via hierarchical patterns. The deep neural network model is based on translating protein sequences and structural information into a musical score that features different pitch...

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Detalles Bibliográficos
Autores principales: Yu, Chi-Hua, Buehler, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078008/
https://www.ncbi.nlm.nih.gov/pubmed/32206742
http://dx.doi.org/10.1063/1.5133026