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BCG as a Case Study for Precision Vaccine Development: Lessons From Vaccine Heterogeneity, Trained Immunity, and Immune Ontogeny

Vaccines have been traditionally developed with the presumption that they exert identical immunogenicity regardless of target population and that they provide protection solely against their target pathogen. However, it is increasingly appreciated that vaccines can have off-target effects and that v...

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Detalles Bibliográficos
Autores principales: Angelidou, Asimenia, Diray-Arce, Joann, Conti, Maria Giulia, Smolen, Kinga K., van Haren, Simon Daniël, Dowling, David J., Husson, Robert N., Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078104/
https://www.ncbi.nlm.nih.gov/pubmed/32218774
http://dx.doi.org/10.3389/fmicb.2020.00332