Osteopontin Upregulates Col IV Expression by Repressing miR-29a in Human Retinal Capillary Endothelial Cells

Abnormal synthesis of extracellular matrix (ECM), especially collagen type IV (Col IV), in human retinal capillary endothelial cells (HRCECs) and resultant basement membrane (BM) thickening is the most prominent and characteristic feature of early diabetic retinopathy (DR). Osteopontin (OPN) has bee...

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Detalles Bibliográficos
Autores principales: Duan, Ping, Chen, Siyu, Zeng, Yuxiao, Xu, Haiwei, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078126/
https://www.ncbi.nlm.nih.gov/pubmed/32182570
http://dx.doi.org/10.1016/j.omtn.2020.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078126/
https://www.ncbi.nlm.nih.gov/pubmed/32182570
http://dx.doi.org/10.1016/j.omtn.2020.02.001

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