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Enhanced osteogenesis and therapy of osteoporosis using simvastatin loaded hybrid system

Postmenopausal osteoporosis is a common chronic dynamic bone disorder, caused by estrogen deficiency. To address this issue, we constructed a controlled drug-release system composed of poly (N-isopropylacrylamide) brush modified mesoporous hydroxyapatite (MHA-SIM-P) loaded with simvastatin (SIM) usi...

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Detalles Bibliográficos
Autores principales: Wu, Tao, Sun, Jing, Tan, Lei, Yan, Qi, Li, Lei, Chen, Liangwen, Liu, Xiangmei, Bin, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078127/
https://www.ncbi.nlm.nih.gov/pubmed/32206736
http://dx.doi.org/10.1016/j.bioactmat.2020.03.004