Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tumor Heterogeneity to Overall Survival

Total tumor size (TS) metrics used in TS models in oncology do not consider tumor heterogeneity, which could help to better predict drug efficacy. We analyzed individual target lesions (iTLs) of patients with metastatic colorectal carcinoma (mCRC) to determine differences in TS dynamics by using the...

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Detalles Bibliográficos
Autores principales: Vera-Yunca, Diego, Girard, Pascal, Parra-Guillen, Zinnia P., Munafo, Alain, Trocóniz, Iñaki F., Terranova, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078147/
https://www.ncbi.nlm.nih.gov/pubmed/32185612
http://dx.doi.org/10.1208/s12248-020-0434-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078147/
https://www.ncbi.nlm.nih.gov/pubmed/32185612
http://dx.doi.org/10.1208/s12248-020-0434-7

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