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Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis

Background and Aims: Monocyte chemotactic protein-1 (MCP-1) is a potent chemoattractant for monocytes. It is involved in pathogenesis of several inflammatory diseases. Hepatic MCP-1 is a readout of macrophage activation. While inflammation is a major driver of liver disease progression, the origin a...

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Detalles Bibliográficos
Autores principales: Queck, Alexander, Bode, Hannah, Uschner, Frank E., Brol, Maximilian J., Graf, Christiana, Schulz, Martin, Jansen, Christian, Praktiknjo, Michael, Schierwagen, Robert, Klein, Sabine, Trautwein, Christian, Wasmuth, Hermann E., Berres, Marie-Luise, Trebicka, Jonel, Lehmann, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078155/
https://www.ncbi.nlm.nih.gov/pubmed/32218781
http://dx.doi.org/10.3389/fimmu.2020.00354