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Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis
Background and Aims: Monocyte chemotactic protein-1 (MCP-1) is a potent chemoattractant for monocytes. It is involved in pathogenesis of several inflammatory diseases. Hepatic MCP-1 is a readout of macrophage activation. While inflammation is a major driver of liver disease progression, the origin a...
Autores principales: | Queck, Alexander, Bode, Hannah, Uschner, Frank E., Brol, Maximilian J., Graf, Christiana, Schulz, Martin, Jansen, Christian, Praktiknjo, Michael, Schierwagen, Robert, Klein, Sabine, Trautwein, Christian, Wasmuth, Hermann E., Berres, Marie-Luise, Trebicka, Jonel, Lehmann, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078155/ https://www.ncbi.nlm.nih.gov/pubmed/32218781 http://dx.doi.org/10.3389/fimmu.2020.00354 |
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