Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction

Conditions of impaired adrenal function and tissue destruction, such as in Addison’s disease, and treatment resistance of adrenocortical carcinoma (ACC) necessitate improved understanding of the pathophysiology of adrenal cell death. Due to relevant oxidative processes in the adrenal cortex, our stu...

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Detalles Bibliográficos
Autores principales: Weigand, Isabel, Schreiner, Jochen, Röhrig, Florian, Sun, Na, Landwehr, Laura-Sophie, Urlaub, Hanna, Kendl, Sabine, Kiseljak-Vassiliades, Katja, Wierman, Margaret E., Angeli, José Pedro Friedmann, Walch, Axel, Sbiera, Silviu, Fassnacht, Martin, Kroiss, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078189/
https://www.ncbi.nlm.nih.gov/pubmed/32184394
http://dx.doi.org/10.1038/s41419-020-2385-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078189/
https://www.ncbi.nlm.nih.gov/pubmed/32184394
http://dx.doi.org/10.1038/s41419-020-2385-4

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