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Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction
Conditions of impaired adrenal function and tissue destruction, such as in Addison’s disease, and treatment resistance of adrenocortical carcinoma (ACC) necessitate improved understanding of the pathophysiology of adrenal cell death. Due to relevant oxidative processes in the adrenal cortex, our stu...
Autores principales: | Weigand, Isabel, Schreiner, Jochen, Röhrig, Florian, Sun, Na, Landwehr, Laura-Sophie, Urlaub, Hanna, Kendl, Sabine, Kiseljak-Vassiliades, Katja, Wierman, Margaret E., Angeli, José Pedro Friedmann, Walch, Axel, Sbiera, Silviu, Fassnacht, Martin, Kroiss, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078189/ https://www.ncbi.nlm.nih.gov/pubmed/32184394 http://dx.doi.org/10.1038/s41419-020-2385-4 |
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