Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation

BACKGROUND: Breast cancer is the second most common cancer in the world. Despite advances in therapies, the mechanisms of resistance remain the underlying cause of morbidity and mortality. Lipoic acid (LA) is an antioxidant and essential cofactor in oxidative metabolism. Its potential therapeutic ef...

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Detalles Bibliográficos
Autores principales: Farhat, Diana, Léon, Sophie, Ghayad, Sandra E., Gadot, Nicolas, Icard, Philippe, Le Romancer, Muriel, Hussein, Nader, Lincet, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078196/
https://www.ncbi.nlm.nih.gov/pubmed/31988347
http://dx.doi.org/10.1038/s41416-020-0729-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078196/
https://www.ncbi.nlm.nih.gov/pubmed/31988347
http://dx.doi.org/10.1038/s41416-020-0729-6

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