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Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation
BACKGROUND: Breast cancer is the second most common cancer in the world. Despite advances in therapies, the mechanisms of resistance remain the underlying cause of morbidity and mortality. Lipoic acid (LA) is an antioxidant and essential cofactor in oxidative metabolism. Its potential therapeutic ef...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078196/ https://www.ncbi.nlm.nih.gov/pubmed/31988347 http://dx.doi.org/10.1038/s41416-020-0729-6 |