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Translation of mouse model to human gives insights into periodontitis etiology

To suggest candidate genes involved in periodontitis, we combined gene expression data of periodontal biopsies from Collaborative Cross (CC) mouse lines, with previous reported quantitative trait loci (QTL) in mouse and with human genome-wide association studies (GWAS) associated with periodontitis....

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Detalles Bibliográficos
Autores principales: Nashef, Aysar, Matthias, Munz, Weiss, Ervin, Loos, Bruno G., Jepsen, Søren, van der Velde, Nathalie, Uitterlinden, André G., Wellmann, Jürgen, Berger, Klaus, Hoffmann, Per, Laudes, Matthias, Lieb, Wolfgang, Franke, Andre, Dommisch, Henrik, Schäfer, Arne, Houri-Haddad, Yael, Iraqi, Fuad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078197/
https://www.ncbi.nlm.nih.gov/pubmed/32184465
http://dx.doi.org/10.1038/s41598-020-61819-0