Extensive splicing changes in an ALS/FTD transgenic mouse model overexpressing cytoplasmic fused in sarcoma

Mutations in RNA-binding proteins (RBPs) such as TAR DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Recent evidence suggests that RNA dysregulation mediated by aberrant RBPs may play a critical rol...

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Detalles Bibliográficos
Autores principales: Ito, Daisuke, Taguchi, Ryota, Deguchi, Maki, Ogasawara, Hideaki, Inoue, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078223/
https://www.ncbi.nlm.nih.gov/pubmed/32184412
http://dx.doi.org/10.1038/s41598-020-61676-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078223/
https://www.ncbi.nlm.nih.gov/pubmed/32184412
http://dx.doi.org/10.1038/s41598-020-61676-x

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