Development of a protein-based system for transient epigenetic repression of immune checkpoint molecule and enhancement of antitumour activity of natural killer cells

BACKGROUND: Immune checkpoint blockade (ICB) therapy improved the prognosis of cancer patients, but general administration of ICBs occasionally induces side effects that include immune-related adverse events and tumour hyper-progression. Here, we established a protein-based system, by which endogeno...

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Detalles Bibliográficos
Autores principales: Teratake, Yoichi, Takashina, Tomoki, Iijima, Kenta, Sakuma, Tetsushi, Yamamoto, Takashi, Ishizaka, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078285/
https://www.ncbi.nlm.nih.gov/pubmed/31959920
http://dx.doi.org/10.1038/s41416-019-0708-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078285/
https://www.ncbi.nlm.nih.gov/pubmed/31959920
http://dx.doi.org/10.1038/s41416-019-0708-y

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