MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer

BACKGROUND: Recent studies have suggested that fatty acid oxidation (FAO) is a key metabolic pathway for the growth of triple negative breast cancers (TNBCs), particularly those that have high expression of MYC. However, the underlying mechanism by which MYC promotes FAO remains poorly understood. M...

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Detalles Bibliográficos
Autores principales: Casciano, Jessica C., Perry, Caroline, Cohen-Nowak, Adam J., Miller, Katelyn D., Vande Voorde, Johan, Zhang, Qifeng, Chalmers, Susan, Sandison, Mairi E., Liu, Qin, Hedley, Ann, McBryan, Tony, Tang, Hsin-Yao, Gorman, Nicole, Beer, Thomas, Speicher, David W., Adams, Peter D., Liu, Xuefeng, Schlegel, Richard, McCarron, John G., Wakelam, Michael J. O., Gottlieb, Eyal, Kossenkov, Andrew V., Schug, Zachary T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078291/
https://www.ncbi.nlm.nih.gov/pubmed/31942031
http://dx.doi.org/10.1038/s41416-019-0711-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078291/
https://www.ncbi.nlm.nih.gov/pubmed/31942031
http://dx.doi.org/10.1038/s41416-019-0711-3

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