Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer’s Disease-Related Pathological Progression in the Hippocampus of App(NL-G-F/NL-G-F) Mice

Growing evidence suggests that oxidative stress due to amyloid β (Aβ) accumulation is involved in Alzheimer’s disease (AD) through the formation of amyloid plaque, which leads to hyperphosphorylation of tau, microglial activation, and cognitive deficits. The dysfunction or phenotypic loss of parvalb...

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Detalles Bibliográficos
Autores principales: Hongo, Nobuko, Takamura, Yusaku, Nishimaru, Hiroshi, Matsumoto, Jumpei, Tobe, Kazuyuki, Saito, Takashi, Saido, Takaomi C., Nishijo, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078363/
https://www.ncbi.nlm.nih.gov/pubmed/32218736
http://dx.doi.org/10.3389/fphar.2020.00307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078363/
https://www.ncbi.nlm.nih.gov/pubmed/32218736
http://dx.doi.org/10.3389/fphar.2020.00307

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