Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle

Defining the pathways that control cardiac development facilitates understanding the pathogenesis of congenital heart disease. Herein, we identify enrichment of a Cullin5 Ub ligase key subunit, Asb2, in myocardial progenitors and differentiated cardiomyocytes. Using two conditional murine knockouts,...

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Detalles Bibliográficos
Autores principales: Yamak, Abir, Hu, Dongjian, Mittal, Nikhil, Buikema, Jan W., Ditta, Sheraz, Lutz, Pierre G., Moog-Lutz, Christel, Ellinor, Patrick T., Domian, Ibrahim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078385/
https://www.ncbi.nlm.nih.gov/pubmed/32179481
http://dx.doi.org/10.1016/j.isci.2020.100959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078385/
https://www.ncbi.nlm.nih.gov/pubmed/32179481
http://dx.doi.org/10.1016/j.isci.2020.100959

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